Article
Epidemiological and bioinformatics analyses of air pollution and genetic susceptibility in aortic stenosis risk.
Nature communications - 5 Jun 2026
Ma Yudiyang, Jiang Qi, Zhang Jing, Yang Yining, Tian Yaohua, Yang Jian
Abstract excerpt
While air pollution is a recognized cardiovascular risk, its specific impact on aortic stenosis (AS) remains poorly characterized. This study investigates the association between air pollution and incident AS, integrating gene-environment interactions and network toxicology. Based on the UK Biobank as the primary cohort, long-term air pollution exposure (per standard deviation increase) is associated with an...
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