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Epigenetic Alterations Induced by Air Pollution: A Key Driver in Atherosclerosis Development.

Cardiovascular toxicology - 1 Sept 2025

Goleij Pouya, Tabari Mohammad Amin Khazeei, Sanaye Pantea Majma, Moradi Ali, Karimi Hossein, Rezaee Aryan, Kumar Alan Prem, Khan Haroon

Abstract excerpt

Air pollution, a global health concern, is linked to atherosclerosis through epigenetic modifications such as DNA methylation, histone modifications, and non-coding RNA regulation. Long-term exposure to air pollution such as particulate matter 2.5 (PM 2.5), polycyclic aromatic hydrocarbons (PAHs), and heavy metals can induce alterations in DNA methylation patterns, especially in genes regulating inflammation and...

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PMID: 40610835
DOI: 10.1007/s12012-025-10036-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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