Article
Fine particles, genetic pathways, and markers of inflammation and endothelial dysfunction: Analysis on particulate species and sources.
Journal of exposure science & environmental epidemiology - 1 Jun 2016
Dai Lingzhen, Bind Marie-Abele, Koutrakis Petros, Coull Brent A, Sparrow David, Vokonas Pantel S, Schwartz Joel D
Abstract excerpt
Studies have found associations between PM2.5 and cardiovascular events. The role of different components of PM2.5 is not well understood. We used linear mixed-effects models with the adaptive LASSO penalty to select PM2.5 species and source(s), separately, that may be associated with markers of inflammation and endothelial dysfunction, with adjustment for age, obesity, smoking, statin use, diabetes mellitus,...
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