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Article

Single Immunoglobulin Interleukin1-Related Receptor-TWIST1 Axis Regulates Barrier Function in Neonatal Intestine.

Cellular and molecular gastroenterology and hepatology - 1 Jan 2026

Venkatraman Aparna, Yu Wei, Menden Heather L, Mabry Sherry M, Wheatley Joshua L, Umar Shahid, Chavez-Bueno Susana, Sampath Venkatesh

Abstract excerpt

BACKGROUND & AIMS: The genetic basis of impaired intestinal barrier function in preterm infants is poorly understood. Variants in single immunoglobulin interleukin1-related receptor, a negative regulator of Toll-like receptor signaling, have been identified in preterm infants with necrotizing enterocolitis. We hypothesized that single immunoglobulin interleukin1-related receptor variants associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Interleukin-1

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Source

Open in PubMed Open full text

Identifiers

PMID: 42248551
DOI: 10.1016/j.jcmgh.2026.101823
PMCID: PMC13380487

Genes

SIGIRR
TWIST1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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