Article
Improving Detection Efficiency of FNAC and BRAF V600E Mutation in Thyroid Nodules Using Pipette Mixing: A Retrospective Study.
Diagnostic cytopathology - 1 Sept 2026
Feng Wanru, Chen Yuanyuan
Abstract excerpt
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy, with a significant subset of cases harboring the BRAF V600E mutation. Fine-needle aspiration cytology (FNAC) combined with BRAF V600E mutation detection is a standard diagnostic approach for thyroid nodules. However, sample heterogeneity often leads to inconsistent results between cytological and molecular analyses. This study...
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