Article
Molecular analysis of residual ThinPrep material from thyroid FNAs increases diagnostic sensitivity.
Cancer cytopathology - 1 Jun 2015
Krane Jeffrey F, Cibas Edmund S, Alexander Erik K, Paschke Ralf, Eszlinger Markus
Abstract excerpt
BACKGROUND: Molecular testing for genetic alterations associated with malignancy is a potential triage approach for thyroid fine-needle aspiration (FNA) samples with indeterminate cytology. Because liquid-based FNA material allows for efficient RNA extraction, the authors analyzed residual material for common point mutations and rearrangements. METHODS: Thyroid FNAs were classified according to The Bethesda...
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