Article
A Retrospective Evaluation of the Diagnostic Performance of an Interdependent Pairwise MicroRNA Expression Analysis with a Mutation Panel in Indeterminate Thyroid Nodules.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2022
Finkelstein Sydney D, Sistrunk John W, Malchoff Carl, Thompson Diane V, Kumar Gyanendra, Timmaraju Venkata Arun, Repko Brittany, Mireskandari Alidad, Evoy-Goodman Lisa Ann, Massoll Nicole A, Lupo Mark A
Abstract excerpt
Background: The addition of genetic analysis to the evaluation of thyroid nodule fine-needle aspiration biopsy samples improves diagnostic accuracy of cytologically indeterminate thyroid nodules (ITNs) with Bethesda III or IV cytopathology. We previously reported the performance of a multiplatform molecular test, referred to in this study as MPTXv1, that includes a mutation panel (ThyGeNEXT®) plus an algorithmic...
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