Article
Significance of FNAC, BRAF mutation, and intraoperative frozen section in surgical decision-making of thyroid nodules.
Diagnostic cytopathology - 1 Jul 2023
Zhu Zhaohui, Su Chang, Chen Guang, Wan Fang, Jin Meishan, Duan Xiumei, Wang Yongxiang, Wang Guimin
Abstract excerpt
BACKGROUND: A preoperative method is desired to discriminate benign from malignant thyroid nodules. This retrospective study evaluated the diagnostic performance of BRAF (B-Raf proto-oncogene) mutation (BRAFV600E ) positivity and fine-needle aspiration cytology (FNAC) relative to intraoperative frozen section pathology. METHODS: Patients underwent preoperative FNAC of thyroid nodules. Cytology specimens were...
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