Article
Molecular classification of thyroid nodules using high-dimensionality genomic data.
The Journal of clinical endocrinology and metabolism - 1 Dec 2010
Chudova Darya, Wilde Jonathan I, Wang Eric T, Wang Hui, Rabbee Nusrat, Egidio Camila M, Reynolds Jessica, Tom Ed, Pagan Moraima, Rigl C Ted, Friedman Lyssa, Wang C Charles, Lanman Richard B, Zeiger Martha, Kebebew Electron, Rosai Juan, Fellegara Giovanni, LiVolsi Virginia A, Kennedy Giulia C
Abstract excerpt
OBJECTIVE: We set out to develop a molecular test that distinguishes benign and malignant thyroid nodules using fine-needle aspirates (FNA). DESIGN: We used mRNA expression analysis to measure more than 247,186 transcripts in 315 thyroid nodules, comprising multiple subtypes. The data set consist...
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