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Feasibility and performance of the Idylla™ NRAS/BRAF cartridge mutation assay on thyroid liquid-based fine-needle aspiration.

Diagnostic cytopathology - 1 Dec 2021

Hamadou Maud, Lopez Jonathan, Benzerdjeb Nazim, Cugnet-Anceau Christine, Schnoering Gwenaelle, Besançon Julie, Mezrag Saliha, Lapras Veronique, Denier Marie-Laure, Descotes Françoise, Decaussin-Petrucci Myriam

Abstract excerpt

BACKGROUND: Thyroid nodules with indeterminate cytology represent up to 30% of cases. Molecular testing is now highly recommended to improve management. This study aimed to evaluate the use of the Idylla™ NRAS/BRAF mutation test, a rapid and automated polymerase chain reaction (PCR) assay validated for fixed paraffin-embedded use, on residual thyroid liquid-based fine-needle aspiration (LB-FNA). METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34698448
DOI: 10.1002/dc.24897

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