[Analysis of HLA and HPA Antibody Specificity and Evaluation of HLA Antigen Immunogenicity in 90 Platelet Transfusion Refractory Patients in Changchun Region].

Abstract excerpt

OBJECTIVE: To detect HLA and HPA antibodies in patients with platelet transfusion refractoriness (PTR) in Changchun region, analyze their specificity, identify the major antibodies responsible for transfusion failure, and evaluate the immunogenicity of HLA antigens, so as to provide a basis for the development of clinical transfusion strategies. METHODS: Blood samples were collected from 90 patients with PTR from...

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