Article

Integrating HLA and HPA in Precision Transfusion: Insights from Platelet Transfusion Refractoriness Driven by Anti-CD36 Alloimmunization and Multifactorial Hemostatic Complications

2025-11-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose:</bold> CD36, recognized as a distinct blood group system, encodes a class-B scavenger receptor essential for hemostasis and innate immunity. Alloantibodies against CD36, although often overlooked, are a significant cause of platelet transfusion refractoriness (PTR), fetal–neonatal alloimmune thrombocytopenia, and immune-mediated bleeding. The comparative effectiveness...

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Literature Corpus work: 27913bd6-fb78-53ae-a138-010a5dc7022c
DOI: 10.21203/rs.3.rs-7551923/v3

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