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[Diversity of HPA Antigen-antibody and Its Application in Platelet Transfusion in Shenzhen Area].

Zhongguo shi yan xue ye xue za zhi - 1 Apr 2026

Xia Wen-Xia, Yang Fan, Che Hua-Tao, Li Xi-Miao, Gao Su-Qing, Xu Yun-Ping

Abstract excerpt

OBJECTIVE: To investigate the polymorphism and genotype frequency of HPA gene in platelet donors in Shenzhen area, and to explore its application in clinical platelet transfusion. METHODS: The blood samples of 461 platelet donors aged 18-55 years old were genotyped for HPA-1~6,-10,-15 and -21 using multiple fluorescent PCR. Platelet-specific antibodies were detected according to the instructions of PAKPLUS kit....

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Identifiers

PMID: 42227437
DOI: 10.19746/j.cnki.issn1009-2137.2026.02.018

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