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Article

Mendelian Randomization Analysis of Psoriasis and Multiparameter Renal Function Trajectories.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Huang Zhihao, Liu Shengxiu

Abstract excerpt

INTRODUCTION: While observational studies suggest that psoriasis may increase the risk of renal impairment, evidence supporting a causal relationship remains inconclusive. This Mendelian randomization (MR) study systematically investigates the genetic causality between psoriasis and multidimensional renal function trajectories, encompassing both static measures and dynamic progression patterns. METHODS: We...

Read the complete abstract on PubMed

Topics

Humans
Psoriasis
Mendelian Randomization Analysis
Glomerular Filtration Rate
Genome-Wide Association Study
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Disease Progression

Renal Insufficiency, Chronic

Finland

Kidney

Risk Factors

Male

Source

Open in PubMed Open full text

Identifiers

PMID: 42227376
DOI: 10.2174/0118715303426134251202143308
PMCID: PMC13670195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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