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Article

Mapping the Causal Landscape of Psoriasis: A Systematic Mendelian Randomization Evidence Synthesis and Development of the MR-PsO Atlas Platform.

Experimental dermatology - 1 May 2026

Lu Jin-Yu, Zeng Wenling, Wang Kexin, Zhou Junlin, Pan Wenhao, Fan Qiaoming, Yang Qingyi, Liu Manting, Ren Kai-Fang

Abstract excerpt

Psoriasis is a complex immune-mediated disease closely linked to multiple systemic comorbidities. Although Mendelian randomization (MR) studies have been widely applied to investigate its potential risk factors, existing evidence remains fragmented and sometimes contradictory, limiting clinical translation. This study aimed to systematically consolidate MR findings on psoriasis and to develop an interactive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42157626
DOI: 10.1111/exd.70272

Genes

APOF
IFNLR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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