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Article

Effects of 25-Hydroxyvitamin D Levels on Renal Function: A Bidirectional Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 17 May 2023

Adi Manel, Ghanbari Faegheh, Downie Mallory L, Hung Adriana, Robinson-Cohen Cassiane, Manousaki Despoina

Abstract excerpt

CONTEXT: Observational studies investigating the role of vitamin D in renal function have yielded inconsistent results. OBJECTIVE: We tested whether 25-hydroxyvitamin D (25[OH]D) serum levels are associated with renal function, and inversely, whether altered renal function causes changes in 25(OH)D, using Mendelian randomization (MR). METHODS: In this two-sample MR study, we used single nucleotide polymorphisms...

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Identifiers

PMID: 36510827
DOI: 10.1210/clinem/dgac724
PMCID: PMC10413421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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