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Article

Genetic Variants and Clinical Characteristics of Young-Onset Parkinson's Disease in the Hakka Population of Western Fujian.

Brain and behavior - 1 Jun 2026

Pan Li-Ying, Guo Fang, Zheng Chong, Hu Xiao-Hong, Chen Yan-Gui, Lin Rong-Rong

Abstract excerpt

RESEARCH OBJECTIVE: Young-onset Parkinson's disease (YOPD), defined by symptom onset at or before 50 years of age, has a strong genetic component. The mutation spectra vary markedly across ethnic groups. However, YOPD among the Hakka, a subgroup of the Han Chinese ethnicity, remains uncharacterized. We investigated the genetic and clinical profiles of YOPD in the Hakka population of western Fujian. MATERIALS AND...

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Source

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Identifiers

PMID: 42204920
DOI: 10.1002/brb3.71504
PMCID: PMC13239422

Genes

PRKN
SNCA
ATP13A2
ATXN2
COQ2
EIF4G1
GBA1
GCH1
NR4A2
PINK1
TENM4
UCHL1
UQCRC1
VPS13C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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