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Impact of Matrix Metalloproteinase-8 Polymorphisms on Nasopharyngeal Carcinoma Risk.

Anticancer research - 1 Sept 2024

Chen Chao-Hsuan, Chin Yu-Ting, Hsu Shih-Wei, Shih Liang-Chun, Tien Hui-Chi, Tsai Chia-Wen, Wang Yun-Chi, Liu Yen-Fang, Bau DA-Tian, Chang Wen-Shin

Abstract excerpt

BACKGROUND/AIM: Upregulation of matrix metallo-proteinase-8 (MMP-8) serves as a protein-based indicator for predicting nasopharyngeal carcinoma (NPC) metastasis. Nevertheless, the role of MMP-8 genotypes in NPC has never been investigated. This study aimed to explore the involvement of MMP-8 genotypes in NPC development. MATERIALS AND METHODS: We employed the polymerase chain reaction-restriction fragment length...

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PMID: 39197904
DOI: 10.21873/anticanres.17207

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