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Article

Upper lung asymmetry identifies distinct clinical phenotypes in idiopathic pleuroparenchymal fibroelastosis.

BMC pulmonary medicine - 25 May 2026

Kinoshita Yoshiaki, Takata Kengo, Hara Keita, Hirai Chiharu, Ikeda Taiki, Utsunomiya Takuhide, Nakashima Shota, Kushima Hisako, Ishii Hiroshi

Abstract excerpt

BACKGROUND: Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a progressive interstitial lung disease characterized by upper lobe-predominant elastofibrosis. While disease asymmetry has been described in other interstitial lung diseases, its clinical significance in IPPFE remains unclear. METHODS: We evaluated 102 patients with IPPFE, 56 with idiopathic pulmonary fibrosis, and 50 healthy controls. Lung...

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PMID: 42178527
DOI: 10.1186/s12890-026-04368-y
PMCID: PMC13377844

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