Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated phenotyping identifies reproducible prognostic subgroups in idiopathic pleuroparenchymal fibroelastosis.

Respiratory research - 26 Jun 2026

Otoshi Ryota, Kitamura Hideya, Oda Tsuneyuki, Kanzawa Akihiro, Okamura Ken, Niwa Takashi, Baba Tomohisa, Iwasawa Tae, Takemura Tamiko, Mizuguchi Kenji, Natsume-Kitatani Yayoi, Ogura Takashi

Abstract excerpt

BACKGROUND: Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare interstitial lung disease characterized by upper-lobe-predominant fibrosis and heterogeneous prognosis. An integrated phenotype classification incorporating clinical, radiological and biological markers has not been established. METHODS: We conducted a retrospective observational study of 32 patients with idiopathic PPFE in an exploratory...

Read the complete abstract on PubMed

Topics

Humans
Female
Phenotype
Retrospective Studies
Male
Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Idiopathic Pulmonary Fibrosis

Aged

Reproducibility of Results

Tomography, X-Ray Computed

Cohort Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42363231
DOI: 10.1186/s12931-026-03780-6
PMCID: PMC13584422

Genes

KL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated phenotyping identifies reproducible prognostic subgroups in idiopathic pleuroparenchymal fibroelastosis.PMID 42363231Read ↗

BAL Transcriptomes Characterize Idiopathic Pulmonary Fibrosis Endotypes With Prognostic ImpactSemantic proximity Read ↗

Phenotypic Clusters Predict Outcomes in a Longitudinal Interstitial Lung Disease Cohort.Semantic proximity Read ↗

Upper lung asymmetry identifies distinct clinical phenotypes in idiopathic pleuroparenchymal fibroelastosis.Semantic proximity Read ↗

Cluster analysis of transcriptomic datasets to identify endotypes of Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Update on the diagnosis and classification of ILD.Semantic proximity Read ↗

Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosisSemantic proximity Read ↗

Serum latent transforming growth factor-β binding protein 4 as a novel biomarker for idiopathic pleuroparenchymal fibroelastosis.Semantic proximity Read ↗

Clinical features of idiopathic pleuroparenchymal fibroelastosis with progressive phenotype showing a decline in forced vital capacity.Semantic proximity Read ↗

Comorbidities in Unclassifiable Interstitial Lung DiseaseSemantic proximity Read ↗

A syndromic framework for progressive pulmonary fibrosis.Semantic proximity Read ↗

Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Identification of Clinical Phenotypes in Idiopathic Interstitial Pneumonia with Pulmonary Emphysema.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.