Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Status of pfcrt and pfmdr1 mutations in Plasmodium falciparum isolates in Gabon in 2019 after chloroquine withdrawal.

Acta tropica - 1 Jul 2026

Dinzouna-Boutamba Sylvatrie-Danne, Iroungou Berthe Amélie, Akombi Falone Larissa, Yacka-Mouele Lauriane, Moon Zin, Lee Sanghyun, Na Byoung-Kuk, Hong Yeonchul, Goo Youn-Kyoung

Abstract excerpt

Chloroquine (CQ) resistance has long contributed to antimalarial treatment failure. Despite the implementation of artemisinin-based combination therapies (ACTs) in Gabon, continued surveillance of antimalarial drug resistance markers remains essential for malaria control and elimination. This study aimed to monitor molecular markers of antimalarial drug resistance, specifically the Plasmodium falciparum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Chloroquine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Malaria, Falciparum

Share to Membrane Transport Proteins

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Identifiers

PMID: 42176722
DOI: 10.1016/j.actatropica.2026.108153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Status of pfcrt and pfmdr1 mutations in Plasmodium falciparum isolates in Gabon in 2019 after chloroquine withdrawal.PMID 42176722Read ↗

Reversal of Chloroquine Resistance in Plasmodium falciparum in Gabon: A Phenotype-Genotype Relationship over the Last 20 Years.Semantic proximity Read ↗

Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania.Semantic proximity Read ↗

Prevalence of Plasmodium falciparum antimalarial drug resistance genes in Southeastern Gabon from 2011 to 2014Semantic proximity Read ↗

Polymorphisms in Pfcrt and Pfmdr-1 genes after five years withdrawal of chloroquine for the treatment of Plasmodium falciparum malaria in West Bengal, India.Semantic proximity Read ↗

Genetic polymorphisms in Plasmodium falciparum chloroquine resistance genes, pfcrt and pfmdr1, in North Sulawesi, Indonesia.Semantic proximity Read ↗

En-route to the 'elimination' of genotypic chloroquine resistance in Western and Southern Zambia, 14 years after chloroquine withdrawal.Semantic proximity Read ↗

Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of chloroquineSemantic proximity Read ↗

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon.Semantic proximity Read ↗

Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicineSemantic proximity Read ↗

Polymorphisms in the parasite genes for pfcrt and pfmdr-1 as molecular markers for chloroquine resistance in Plasmodium falciparum in Lambaréné, Gabon.Semantic proximity Read ↗

The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan Region, Southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt geneSemantic proximity Read ↗

Decreased prevalence of the Plasmodium falciparum Pfcrt K76T and Pfmdr1 and N86Y mutations post-chloroquine treatment withdrawal in Katete District, Eastern Zambia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.