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Article

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon.

Malaria journal - 27 Mar 2017

Ndam Nicaise Tuikue, Basco Leonardo K, Ngane Vincent Foumane, Ayouba Ahidjo, Ngolle Eitel Mpoudi, Deloron Philippe, Peeters Martine, Tahar Rachida

Abstract excerpt

BACKGROUND: Chloroquine had been used extensively during the last five decades in Cameroon. Its decreasing clinical effectiveness, supported by high proportions of clinical isolates carrying the mutant pfcrt haplotype (CVIET), led the health authorities to resort to amodiaquine monotherapy in 2002 and artemisinin-based combination therapy (ACT) in 2004 (artesunate-amodiaquine, with artemether-lumefantrine as an...

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Identifiers

PMID: 28347314
DOI: 10.1186/s12936-017-1783-2
PMCID: PMC5368939

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