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Article

Reversal of Chloroquine Resistance in Plasmodium falciparum in Gabon: A Phenotype-Genotype Relationship over the Last 20 Years.

International journal of molecular sciences - 16 Apr 2026

Inoue Juliana, Rodi Miriam, Bohissou Francis Emmanuel Towanou, de Carvalho Lais Pessanha, Lohse Katharina, Koehne Erik, Agnandji Selidji T, Mombo-Ngoma Ghyslain, Kremsner Peter G, Kreidenweiss Andrea, Held Jana

Abstract excerpt

The emergence of chloroquine-resistant Plasmodium falciparum in the 1950s posed a global threat to malaria control. Ceasing chloroquine use restored chloroquine-sensitive strains in many African countries. To assess whether chloroquine sensitivity re-emerged in Lambaréné, Gabon, we compiled published and new data on P. falciparum ex vivo chloroquine susceptibility, quantified as half-maximal inhibitory...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42074206
DOI: 10.3390/ijms27083566
PMCID: PMC13116125

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