A Viral-Host Immunogenetic Interaction Model in Hodgkin Lymphoma: Co-Association of HHV-6B Infection and IL-18 rs1946518 Polymorphism.

doi:10.31557/APJCP.2026.27.5.1931

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Article

A Viral-Host Immunogenetic Interaction Model in Hodgkin Lymphoma: Co-Association of HHV-6B Infection and IL-18 rs1946518 Polymorphism.

Asian Pacific journal of cancer prevention : APJCP - 1 May 2026

Alheany Aya Raed Abdulwahhab, Abdulkareem Aws Zamil, Abdullah Zahraa Ali, Al-Alwany Shakir H Mohammed

Abstract excerpt

BACKGROUND: Hodgkin lymphoma (HL) arises from germinal center B cells through complex viral, genetic, and environmental factors. This study examines HHV-6B infection and the IL-18 rs1946518 polymorphism as potential contributors to inflammation-driven HL susceptibility and risk of disease progression. METHODS: A case-control study of 180 venous blood samples was conducted, including 90 HL patients and 90 healthy...

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PMID: 42169600
DOI: 10.31557/APJCP.2026.27.5.1931

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