Article
The Dual Role of ABCG2 Copy Number Variation: A Protective Factor in Cancer Risk, and a Prognostic Marker for Survival in Thai Breast Cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 May 2026
Sophonnithiprasert Thanet, Pongtheerat Tanett, Saelee Pensri
Abstract excerpt
OBJECTIVE: This study aimed to investigate CNVs of MDR1 and ABCG2 and their associations with clinicopathological characteristics and survival outcomes in Thai breast cancer patients. METHODS: Genomic DNA from 126 breast cancer patients and 162 healthy controls was analyzed. CNVs were determined using real-time PCR and the ∆Ct method. Associations with clinicopathological parameters were assessed using the...
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