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Article

Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy

1 Jul 2016

Abstract excerpt

BACKGROUND: The cellular autophagic response to radiation is complex. Various cells and tissues respond differentially to radiation, depending on both the dose of exposure and the time post irradiation. In the current study, we determined the autophagosomal and lysosomal response to radiation in lung cancer cell lines by evaluating the expression of the associated proteins, as well as the effect of relevant gene...

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PMID: 27380135
DOI: 10.1038/bjc.2016.202

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