Article
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy.
Cancer research - 1 Mar 2008
Apel Anja, Herr Ingrid, Schwarz Heinz, Rodemann H Peter, Mayer Andreas
Abstract excerpt
Autophagy or "self eating" is frequently activated in tumor cells treated with chemotherapy or irradiation. Whether autophagy represents a survival mechanism or rather contributes to cell death remains controversial. To address this issue, the role of autophagy in radiosensitive and radioresistan...
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