Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malignant reninoma with pulmonary metastasis and ATRX mutation treated with olaparib: a case report of specialized treatment.

Frontiers in immunology - 1 Jan 2026

Zi Guo Run, Zhang Da-Jiang, He Dong-Lin, Feng Run-Lin, Ke Chang-Xing

Abstract excerpt

We report a rare case of 32-year-old female with malignant reninoma complicated by pulmonary metastasis and ATRX mutation (p.G1964*, VAF 23.73%), initially misdiagnosed as renal pelvic carcinoma and treated with radical left nephrectomy and ureterectomy. The patient developed local recurrence and pancreatic head metastasis in January 2025, with stable disease achieved after radiotherapy, EP chemotherapy and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Renin
Share to Kidney Neoplasms
Share to Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phthalazines

Share to Piperazines

Share to Poly(ADP-ribose) Polymerase Inhibitors

Share to Treatment Outcome

Share to X-linked Nuclear Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 42158855
DOI: 10.3389/fimmu.2026.1803771
PMCID: PMC13180741

Genes

ATRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Malignant reninoma with pulmonary metastasis and ATRX mutation treated with olaparib: a case report of specialized treatment.PMID 42158855Read ↗

The (pro)renin receptor: a novel biomarker and potential therapeutic target for various cancersSemantic proximity Read ↗

Targetable NOTCH1 rearrangements in reninomaSemantic proximity Read ↗

DAXX is associated with early recurrence of pancreatic neuroendocrine tumors after R0 resection.Semantic proximity Read ↗

[ELOC-mutated renal cell carcinoma with new mutation site combined with lung adenocarcinoma: report of a case].Semantic proximity Read ↗

Gastric metastasis of renal cell carcinoma and molecular targeted therapy: a case reportSemantic proximity Read ↗

POLR2A Drives Tumor Cell Aggressive in Both VHL and PBRM1 Mutation Renal-Cell CarcinomaSemantic proximity Read ↗

A Case-Inspired Exploration of Renin Mutations in Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD): Not All Paths Lead to the ER.Semantic proximity Read ↗

A review on the role of PRNCR1 in human disorders with an especial focus on cancer.Semantic proximity Read ↗

Association between hepatic angiosarcoma and end-stage renal disease: nationwide population-based evidence and enriched mutational signature of aristolochic acid exposure.Semantic proximity Read ↗

Metastatic malignant PEComa of the leg with identification of ATRX mutation by next-generation sequencing.Semantic proximity Read ↗

Neuropilin 1 and Neuropilin 2 Gene Invalidation or Pharmacological Inhibition Reveals Their Relevance for the Treatment of Metastatic Renal Cell CarcinomaSemantic proximity Read ↗

Neuropilin 1 and Neuropilin 2 Gene Invalidation or Pharmacological Inhibition Reveals Their Relevance for the Treatment of Metastatic Renal Cell CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.