Article
A novel core genome clustering method proposed for population structure analysis and genotyping of bacterial genomes.
Journal of microbiological methods - 1 Jul 2026
Zhang Yuyan, Pan Qiuhui
Abstract excerpt
Core genome multilocus sequence typing (cgMLST) has emerged as an effective method for population structure analysis and genotyping. However, it exhibits limited discriminative power for bacterial genomes that are highly recombinogenic or display low genetic diversity. To address this limitation, we propose cgKNV, a novel core genome clustering method based on the k-mer natural vector, which overcomes the...
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