Article
Myocardial YBX1 is dispensable for cardiac development and function.
American journal of physiology. Heart and circulatory physiology - 1 Jun 2026
Stanley Elise V, Han Zhijie, Sassower Reaghan, Gao Chao, Kessinger Chase W, Wu Tongbin
Abstract excerpt
The Y-box-binding protein 1 (YBX1) is a DNA- and RNA-binding protein with multifaceted roles in transcriptional, posttranscriptional, and translational regulation. Consequently, YBX1 controls many aspects of cellular function, including proliferation, differentiation, and apoptosis. In recent years, YBX1 emerged as an important player in the cardiovascular system, whose dysregulation underlies many forms of heart...
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