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Article

Deficiency of the RNA-binding protein RBMS1 improves myocardial fibrosis and heart failure

16 May 2025

Abstract excerpt

BACKGROUND AND AIMS: Previous studies have highlighted the significance of RNA-binding proteins and alternative splicing (AS) in the progression of complex diseases, but the specific involvement of AS in heart failure (HF) remains unclear. This study aimed to elucidate the role of RNA-binding motif single-stranded interacting protein 1 (RBMS1), an RNA-binding protein, in the development of HF by regulating AS and...

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PMID: 40471706
DOI: 10.1093/eurheartj/ehaf370

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