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Article

Osteoarthritis and depression a bidirectional TwoSample Mendelian randomization study on genetic causal association.

BMC musculoskeletal disorders - 18 May 2026

Chen Haozhu, Tan Jinmei, Zhang Kaiwei

Abstract excerpt

BACKGROUND: Epidemiological observations suggest a potential causal relationship between osteoarthritis and depression. Alternatively, this association might arise from the simple co-occurrence of osteoarthritis and depression due to shared genetic or environmental risk factors within the population. However, the causal nature of this relationship remains uncertain. This study aims to investigate the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42151986
DOI: 10.1186/s12891-026-09872-0
PMCID: PMC13361587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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