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Article

Genomic context of mutations in MIR142 in blood cancers: summary and integrative analysis.

Cellular & molecular biology letters - 18 May 2026

Wegorek Wladyslaw, Tire Adrian, Kuznicki Daniel, Richter Julia, Giefing Maciej, Klapper Wolfram, Kozlowski Piotr, Galka-Marciniak Paulina

Abstract excerpt

MIR142 is the most frequently mutated microRNA (miRNA) gene in cancer, with recurrent alterations observed particularly in hematologic malignancies of lymphoid origin. It is expressed at very high levels in blood cells and plays an essential role in the development, differentiation, and maturation of various lymphopoietic and hematopoietic lineages. To gain a deeper understanding of MIR142 mutations, we summarize...

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PMID: 42151759
DOI: 10.1186/s11658-026-00933-9
PMCID: PMC13435480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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