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Article

Natural variations in small RNA origin loci generate circuit diversity underlying temperature acclimation in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 2026

Okahata Misaki, Iki Taichiro, Yoshina Sawako, Minakuchi Yohei, Mori Yukina, Sawada Natsumi, Miura Toru, Kai Toshie, Toyoda Atsushi, Mitani Shohei, Ohta Akane, Kuhara Atsushi

Abstract excerpt

Individuals respond differently to environmental cues because of inherent variations in genome sequences. This study demonstrates that natural variation in small RNA (sRNA) within embryos epigenetically shapes adaptive neural circuits underlying diverse animal temperature acclimation. We performed comparative genome profiling of Caenorhabditis elegans variants with differential temperature acclimation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42150066
DOI: 10.1073/pnas.2538076123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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