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Article

Early experiences mediate distinct adult gene expression and reproductive programs in Caenorhabditis elegans.

PLoS genetics - 1 Feb 2018

Ow Maria C, Borziak Kirill, Nichitean Alexandra M, Dorus Steve, Hall Sarah E

Abstract excerpt

Environmental stress during early development in animals can have profound effects on adult phenotypes via programmed changes in gene expression. Using the nematode C. elegans, we demonstrated previously that adults retain a cellular memory of their developmental experience that is manifested by differences in gene expression and life history traits; however, the sophistication of this system in response to...

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Identifiers

PMID: 29447162
DOI: 10.1371/journal.pgen.1007219
PMCID: PMC5831748

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