Article
Achieving improved accuracy for imputation of ancient DNA.
Bioinformatics (Oxford, England) - 1 Jan 2023
Ausmees Kristiina, Nettelblad Carl
Abstract excerpt
MOTIVATION: Genotype imputation has the potential to increase the amount of information that can be gained from the often limited biological material available in ancient samples. As many widely used tools have been developed with modern data in mind, their design is not necessarily reflective of the requirements in studies of ancient DNA. Here, we investigate if an imputation method based on the full...
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