Article
Robust imputation-based method for eye, hair, and skin colour prediction from low-coverage ancient DNA.
Scientific reports - 5 Feb 2026
Maróti Zoltán, Nyerki Emil, Török Tibor, Varga Gergely István, Kalmár Tibor
Abstract excerpt
The prediction of externally visible traits (eye, hair, and skin colours) from DNA can provide valuable information for contemporary and ancient human populations. The validated HIrisPlex-S method is the primary tool in forensics for phenotyping modern samples. The HIrisPlex-S multiplex PCR assay can handle trace DNA from modern samples, but the analysis of degraded, low-coverage ancient DNA (aDNA) presents...
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