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Article

The Causal Relationship between Blood Cell Traits and Valvular Heart Disease: A Two-Sample Mendelian Randomization Study.

Arquivos brasileiros de cardiologia - 1 Mar 2026

Wu Xiaoli, Li Yufeng, Tian Jinyu

Abstract excerpt

BACKGROUND: The pathogenesis of valvular heart disease (VHD) remains unclear, highlighting the need for further research on risk factors. OBJECTIVES: To explore the potential causal links between blood cell traits and four types of VHD: rheumatic heart disease, mitral valve disease, aortic valve disease, and tricuspid valve disease. METHODS: This study utilized summary statistics from large-scale GWAS and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42138859
DOI: 10.36660/abc.20250063
PMCID: PMC13128221

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