Article
[Association of single-nucleotide variants of ABCG2 and ABCB1 genes with clinical and laboratory parameters during clozapine therapy].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2026
Kidyaeva A V, Tulendinov E R, Agaev A M, Nasyrova R F
Abstract excerpt
OBJECTIVE: To evaluate the relationship between low-functioning single-nucleotide variants of rs1045642, rs1128503, and rs2032582 of the ABCB1 gene and rs2231142 of the ABCG2 gene and clinical and laboratory parameters in patients with schizophrenia taking clozapine. MATERIAL AND METHODS: The study included 129 patients with paranoid schizophrenia (F20.0, ICD-10) treated with clozapine. Genotyping was performed...
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