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Article

Effects of age and APOE ϵ4 genotype on the relationship between pulse pressure and executive function in older adults without dementia.

Journal of the International Neuropsychological Society : JINS - 1 May 2026

Quiring Melanie L, Edwards Lauren, Bangen Katherine J, Ho Emily H, Carlsson Cynthia M, Galasko Douglas, Weintraub Sandra, Gershon Richard, Salmon David P

Abstract excerpt

OBJECTIVES: Pulse pressure (PP) calculated as systolic minus diastolic blood pressure is a surrogate measure of arterial stiffness that may affect executive function; however, this relationship could be moderated by age and genetic risk for Alzheimer's disease (AD). We therefore examined relationships among PP, age, AD risk (i.e., APOE genotype) and executive function measured by the NIH Toolbox Cognition Battery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42124479
DOI: 10.1017/S1355617726102008
PMCID: PMC13175078

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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