Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia.

doi:10.1186/s13195-021-00851-2

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Article

Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia.

Alzheimer's research & therapy - 1 Jul 2021

Bangen Katherine J, Smirnov Denis S, Delano-Wood Lisa, Wierenga Christina E, Bondi Mark W, Salmon David P, Galasko Douglas

Abstract excerpt

BACKGROUND: Arterial stiffening has emerged as an important risk factor for Alzheimer's disease (AD) and related dementias. Carotid-femoral pulse wave velocity has been proposed as a non-invasive and reproducible method to assess arterial stiffness. However, the association of pulse wave velocity with performance across multiple cognitive domains as well as interactions with in vivo AD biomarkers and...

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PMID: 34210365
DOI: 10.1186/s13195-021-00851-2
PMCID: PMC8246656

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