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Article

CPNE1 modulates Parkinson's disease risk through peripheral immune cell function: a cross-tissue and single-cell causal inference study.

Mammalian genome : official journal of the International Mammalian Genome Society - 11 May 2026

Zhao Jing, Fu Jia, Zhang Jingjing, Zhang Zhongchi, Bai Xue, Yao Lifen

Abstract excerpt

It has been increasingly recognized that, to a significant extent, the peripheral immune system is playing a role in the etiology of Parkinson’s disease (PD). It has been reported recently that there may be multiple types of genetic susceptibility factors influencing the risk of PD through alterations in the functions of particular immune cells; at present, the precise mechanisms involved remain unclear. Based on...

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Identifiers

PMID: 42115417
DOI: 10.1007/s00335-026-10236-1

Genes

CPNE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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