Article
A new mathematical model for genetic linkage and recombination of haploid virus populations.
Genetics - 6 Jul 2026
Feehley Patrick J, Feehley Michael C, Hsieh Zih-Yu, Poyer Alex T, Contreras Gregory P, Yeh Ting-Yu
Abstract excerpt
Linkage disequilibrium (LD), logarithm of the odds (LOD), and recombination frequency (Rf) have long been measured independently. However, their relationship in viral haploid recombination has not been fully understood due to the unavailability of population-wide sequencing data until recently. Here, we provide the first mathematical model of haploid LOD and Rf, LODF, and RfF, using recombinant single-nucleotide...
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