Article
Rapid haplotype inference for nuclear families.
Genome biology - 1 Jan 2010
Williams Amy L, Housman David E, Rinard Martin C, Gifford David K
Abstract excerpt
Hapi is a new dynamic programming algorithm that ignores uninformative states and state transitions in order to efficiently compute minimum-recombinant and maximum likelihood haplotypes. When applied to a dataset containing 103 families, Hapi performs 3.8 and 320 times faster than state-of-the-ar...
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