Article
A statistical model for genetic mapping of viral infection by integrating epidemiological behavior.
Statistical applications in genetics and molecular biology - 1 Jan 2009
Li Yao, Berg Arthur, Chang Myron N, Du Ping, Ahn Kwangmi, Mauger David, Liao Duanping, Wu Rongling
Abstract excerpt
Large-scale studies of genetic variation may be helpful for understanding the genetic control mechanisms of viral infection and, ultimately, predicting and eliminating infectious disease outbreaks. We propose a new statistical model for detecting specific DNA sequence variants that are responsible for viral infection. This model considers additive, dominance and epistatic effects of haplotypes from three...
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