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Article

MBD8 is required for LDL2-mediated transcriptional repression downstream of H3K9me2 in Arabidopsis.

Nucleic acids research - 5 May 2026

Mori Shusei, Osakabe Akihisa, Juliarni, Tanaka Yuriko, Hirayama Mami, Inagaki Soichi, Kakutani Tetsuji

Abstract excerpt

Histone H3 lysine 9 methylation (H3K9me) is a conserved epigenetic mark for transcriptional gene repression. In Arabidopsis, H3K9 dimethylation (H3K9me2) promotes the removal of a transcription-associated mark, H3K4 monomethylation (H3K4me1), and this process within genes requires the histone demethylase LDL2. However, how LDL2 specifically functions in genes that accumulate H3K9me2 remains unknown. Here, we show...

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Identifiers

PMID: 42107973
DOI: 10.1093/nar/gkag361
PMCID: PMC13157976

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GC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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