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Air Pollution, Lifestyle, and Genetic Risk: A Multidimensional Study of PM2.5 Constituents and Prostate Cancer.

The Journal of urology - 1 May 2026

Zhang Feifei, Zhou Jingcheng, Yang Chao, Wei Shaoqing, Ma Jiahui

Abstract excerpt

PURPOSE: To investigate the associations between long-term exposure to PM2.5 chemical constituents and incident prostate cancer, considering potential effect modification by genetic susceptibility and lifestyle. MATERIALS AND METHODS: We conducted a prospective study of 224,272 male participants from the UK Biobank with a median follow-up of 13.7 years. Individual exposures to PM2.5 and its 5 key constituents...

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Air Pollutants
Air Pollution
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Genetic Risk Score
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PMID: 41528828
DOI: 10.1097/JU.0000000000004920

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