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Article

Occult HBV among anti-HBc-reactive blood donors in Colombia: low HBsAg prevalence, genotype F3, and small-S variation relevant to HBsAg detectability.

Scientific reports - 9 May 2026

Bautista-Amorocho Henry, Silva-Sayago Jorge Alexander, Castellanos-Domínguez Yeny Zulay

Abstract excerpt

PURPOSE: Occult hepatitis B infection (OBI) can sustain residual transfusion risk because HBV DNA may persist at very low levels while HBsAg remains undetectable by routine serology. We assessed OBI among anti-HBc-reactive, HBsAg-negative (anti-HBc+/HBsAg-) donors in Bucaramanga, Colombia and characterized small-S variation within genotype F3. METHODS: In 2021, we analyzed 61,188 donations in three licensed blood...

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Identifiers

PMID: 42106446
DOI: 10.1038/s41598-026-52530-7
PMCID: PMC13346989

Genes

F3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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