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Article

High-Frequency Notable HBV Mutations Identified in Blood Donors With Occult Hepatitis B Infection From Heyuan City of Southern China.

Frontiers in immunology - 1 Jan 2022

Ye Xianlin, Liu Lihua, Chen Lina, Nie Xianghui, Huang Lu, Ye Denghuang, Zeng Jinfeng, Li Tong, Li Bin, Xu Min, Chen Limin

Abstract excerpt

Background: All Chinese blood centers have implemented mini pool (MP) HBV nucleic acid testing (NAT) together with HBsAg ELISA in routine donor screening since 2015. The prevalence of occult hepatitis B virus infection (OBI) in donors from different regions varies, and the molecular characterization of the HBV DNA and clinical outcomes of these OBIs remain largely unexplored. Methods: Blood donations from Heyuan...

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Identifiers

PMID: 35634299
DOI: 10.3389/fimmu.2022.754383
PMCID: PMC9136029

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