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Article

Incidence of Occult Hepatitis B Infection (OBI) and hepatitis B genotype characterization among blood donors in Cameroon.

PloS one - 1 Jan 2024

Mbencho Macqueen Ngum, Hafza Nourhane, Cao Le Chi, Mingo Victorine Ndiwago, Achidi Eric A, Ghogomu Stephen Mbigha, Velavan Thirumalaisamy P

Abstract excerpt

BACKGROUND: Occult hepatitis B infection (OBI) is characterized by the presence of hepatitis B virus (HBV) DNA at low levels in serum (<200 IU/mL) with a negative hepatitis B surface antigen (HBsAg) test. OBI remains a major challenge to blood safety, particularly in HBV-endemic regions like Cameroon, where HBV detection relies solely on HBsAg testing. This cross-sectional study aimed to investigate the actual...

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Identifiers

PMID: 39413100
DOI: 10.1371/journal.pone.0312126
PMCID: PMC11482724

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